Search Results for "ioannidis"

  1. Screening for disease in people without symptoms: The reality
    One of the most contentious questions that come up in science-based medicine that we discuss on this blog is the issue of screening asymptomatic individuals for disease. The most common conditions screened for that we, at least, have discussed on this blog are cancers (e.g., mammography for breast c…
  2. Skeptic’s Guide to Debunking Claims about Telomeres in the Scientific and Pseudoscientific Literature
    The New Year starts with telomeres as the trendiest of trendy biomarkers. As seen in Time, telomeres are the means to monitor our well-being so we can protect ourselves from all sorts from threats, including early death. A skeptic needs to do considerable homework in order to muster the evidence nee…
  3. Mel asks and I do my best to answer.
    Several snarks were painfully maimed in the writing of this blog post I read a lot of the pseudo-medical websites. The writing is at best pedestrian, often turgid, and, at its worst, incoherent. It is rarely either engaging or clever. Wit, the clever bon mot, the amusing turn of phrase or retort, …
  4. Chaperones Needed
    Dr. Oz, one half of the You Doctors. And a professor. A professor. I receive a monthly newsletter from my medical board. Among other issues discussed are the results of disciplinary actions for physicians. Occasionally a physician who has boundary issues is required to have a chaperone present whe…
  5. Do doctors pay attention to negative randomized clinical trials?
    We at the Science-Based Medicine blog believe that all medicine, regardless of where it comes from, should be held to a single science-based standard with regards to efficacy, effectiveness, and safety. We tend to focus primarily on “complementary and alternative medicine” (CAM), now more commo…
  6. Acupuncture Vignettes
    I seem to be writing a lot about acupuncture of late. As perhaps the most popular pseudo-medicine, there seems to be more published on the topic. I have a lot of internet searches set up to automatically feed me new information on various SCAMs. Interestingly, all the chiropractic updates seem to be…
  7. Acupuncture Whac-a-Mole ™
    Those who cannot remember the past are condemned to repeat it. – George Santayana Most people don’t have that willingness to break bad habits. They have a lot of excuses and they continue to produce bad clinical studies. – Carlos Santana (Well, not the last 4 words.) One is a guit…
  8. Everything Causes Cancer
    It’s likely you know someone who has bought into the notion that nutrition is everything, the source of all health and the cause of all illness. Nutrition is very important, to be sure, but it is only one of many possible causes of disease, and if you live in a Western industrialized nation you pr…
  9. The Science of Clinical Trials
    Science-based medicine is partly an exercise in detailed navel gazing – we are examining the use of science in the practice of medicine. As we use scientific evidence to determine which treatments work, we also have to examine the relationship between science and practice, and the strengths an…
  10. “Postnatal depression blood test breakthrough” or Churnalism?
    “Postnatal depression blood test breakthrough” proclaimed the headline. The UK Guardian article then declared: British doctors reveal ‘extremely important’ research that could help tens of thousands of women at risk. Here it comes. Readers were going to be fed a press release generat…
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