Tag: clinical trials

Macular degeneration

Pegcetacoplan (Syfovre™) for macular degeneration: an update

SBM's guest contributor and ophthalmologist, Dr. David Weinberg, provides an update on the phase 3 trials of pegcetacoplan for macular degeneration. The results are still disappointing.

/ January 11, 2024
EBM hierarchy

2023: The year that the evidence-based medicine (EBM) paradigm was weaponized against vaccines and public health

Evidence-based medicine (EBM) has been a very useful paradigm for assessing evidence in medicine. However, like any other framework, it can be misused, particularly when fundamentalist EBM methodolatry leads to its inappropriate application to questions for which it is ill-suited, a misuse that has been weaponized against public health during the pandemic.

/ January 1, 2024

Pegcetacoplan, a new treatment for macular degeneration

FDA approves a new treatment for macular degeneration: the good, the bad, and the disappointing.

/ June 6, 2023

The Polypill Comes of Age

The polypill is effective for secondary prevention of cardiovascular disease. By combining drugs in a single pill, it improves convenience and compliance.

/ September 20, 2022
Pulse oximeters

COVID-19 puts the spotlight on an unexpected racial disparity in health care

Evidence increasingly suggests that pulse oximeters, the little finger clips that measure blood oxygen, overestimate the blood oxygenation in Black patients. It's a problem that's been discussed a long time that took a pandemic to bring to public consciousness. How can SBM decrease or eliminate such healthcare disparities?

/ July 18, 2022

Gender-Affirming Care is Not Experimental, Part II

A lot of the "facts" about providing healthcare to transgender youth turn out to be not actually facts. We present here a summary of the evidence relating to transition-related health care for transgender adolescents.

Homeopathy and Pre-Registered Trials

Preregistering clinical trials is a great idea, but we have to actually track registration.

/ May 18, 2022
Signos Glucose Monitor

Signos Sells a Continuous Glucose Monitor, But Not to Diabetics

Signos is asking customers to pay for the privilege of testing their glucose monitoring system.

/ May 17, 2022
The Good, The Bad, and The Ugly

How to design high quality acupuncture trials: The Good, The Bad, and The Ugly

Acupuncture advocates have published guidelines for "rigorous" acupuncture randomized controlled trials. While that sounds good on the surface, the devil is in the details, which reveal that the dedication to scientific rigor is perhaps not so strong.

/ April 11, 2022