Results for: Ioannidis

p_value

0.05 or 0.005? P-value Wars Continue

The p-value is under fire yet again, but this time with some quick-and-dirty solutions (and some long-and-onerous ones too) to the problems created by relying on this quick-and-dirty test.

/ August 2, 2017
Yoga

Can mind-body practices “reprogram” our DNA?

A recent systematic review has been touted as demonstrating that "mind-body" practices like yoga can reprogram our DNA. There are several reasons to doubt these claims, not the least of which is the history of bias in past studies on this topic.

/ June 26, 2017
EBMupdated

Responding to SBM Critics

A response to a critic of SBM, and setting the record straight on our actual positions regarding evidence and the practice of medicine.

/ April 19, 2017
Donald Trump

Medical science policy in the U.S. under Donald Trump eighty days in

A week after Donald Trump was elected, I speculated about how he would affect medical science policy. Now, 80 days into the Trump administration, we have some observations.

/ April 10, 2017
https://www.flickr.com/photos/euromagic/2351628831/

Peanut Allergy Prevention Advice Does a 180

New guidelines suggest that preventing peanut allergies may be as simple as giving peanut-containing food, beginning in infancy. How did old guidelines, which recommended avoidance, get it so wrong?

/ January 12, 2017
Exercise

Diet and exercise versus cancer: A science-based view

Yes, diet and exercise can be useful to prevent some cancers. Unfortunately, they don't prevent all cancers, and the effect size is more modest than often represented. That's not to say that eating right and exercise aren't good. They are, for so many other reasons than cancer. Just don't view them as a panacea for preventing cancer.

/ September 19, 2016
Cancer cell immunofluorescence

Is there a reproducibility “crisis” in biomedical science? No, but there is a reproducibility problem

Reproducibility is the key to scientific advancement. It has been claimed that we suffer from a "reproducibility crisis," but in reality it is a chronic problem in reproducibility. Here we will look at the scope of the problem and strategies to address it.

/ June 6, 2016
Hijack

The hijacking of evidence-based medicine

A hero of the blog, John Ioannidis, worries that evidence-based medicine has been hijacked, and when Ioannidis says something we at SBM listen. But has EBM been "hijacked"?

/ March 21, 2016

Is scientific peer review a “sacred cow” ready to be slaughtered?

I’ve frequently noted that one of the things most detested by quacks and promoters of pseudoscience is peer review. Creationists hate peer review. HIV/AIDS denialists hate it. Anti-vaccine cranks like those at Age of Autism hate it. Indeed, as a friend of mine, Mark Hoofnagle, pointed out several years ago, pseudoscientists and cranks of all stripes hate it. There’s a reason for...

/ December 21, 2015

American Academy of Family Physicians Home Study Course Recommends Non-Science-Based Treatments

Since passing my board exams in family practice in 1979 I have relied heavily on the American Academy of Family Physicians for continuing medical education via the American Family Physician and the AAFP home study programs. The AAFP prides itself on its evidence-based approach to medicine. In general, it delivers. But the recent FP Essentials Number 432 on “Chronic Pain Management” fell...

/ November 24, 2015