I’ve spent the last three weeks writing about a “brave maverick doctor” by the name of Stanislaw Burzynski who claims that he can cure cancers that regular oncologists cannot. He uses a combination of what he calls “antineoplastons” (which, it turns out, are more or less than the active metabolites of an orphan drug known as sodium phenylbutyrate) plus a very expensive cocktail of chemotherapy and targeted agents chosen in a haphazard fashion and thrown together with little rhyme or reason. This week, I had planned to move on. However, I felt that I had to mention the Burzynski saga because it provides me with the most appropriate segue to a topic I’ve been meaning to write about for a long time, possibly since this blog began. In fact, it’s about as perfect a framework as I can think of upon which to drape the points I want to make in this post.
What I will discuss is perhaps the most effective, devastating attack that proponents of quackery, woo, and nonsense aim at supporters of science-based medicine (SBM). As far as that is the case, it is not effective because it’s fact-based, evidence-based, or science-based. Far from it. Rather, it’s effective because it appeals to the emotions and very effectively demonizes SBM proponents to the point where they often have a hard time standing their ground when it is used. Sometimes, it preemptively prevents them from even speaking up in the first place. It’s a little tactic that I like to call the “compassion gambit,” which means trying to discredit critics of “alternative” medicine by painting them as cold, unfeeling, uncaring, arrogant monsters who want to hurt or kill children (and probably get a big smile on their faces when they torture puppies, to boot). (more…)
Each of the 50 states and the District of Columbia require vaccination against certain diseases as a prerequisite to public and private school attendance, most commonly polio, mumps, measles, diphtheria, rubella, chicken pox, Heamophilus influenza type b, pertussis, tetanus, pneumococcal disease and hepatitis B. Unfortunately, mandatory vaccination for home-schooled children is rare. (1)
All states provide medical exemptions to vaccination mandates for those for whom vaccination poses a health threat. Indeed, it is doubtful that a state could constitutionally deny such medical exemptions.
Forty-eight states also allow exemptions based on religious beliefs. While it might be assumed that religious exemptions are required by the protection afforded religion under the First Amendment to the U.S. Constitution that is not the case. The opposite is true. Religious exemptions themselves are constitutionally suspect. In fact, to pass First Amendment muster, a state’s religious exemption statute may have to be so broad as to become, in essence, a “philosophical” exemption.
Vaccination mandates survive early challenges
Compulsory vaccination laws have enjoyed strong support in the state and federal courts for over a century. Early in the 20th century, the U.S. Supreme Court considered the constitutionality of a statute authorizing a municipal board of health to require and enforce vaccination, in this case during a smallpox epidemic. The Court found the legislation represented a valid exercise of the state’s police power. In a statement that proved prescient about the failed constitutional challenges to vaccination mandates which followed, the Court said that “we do not perceive that this legislation has invaded any right secured by the Federal Constitution.” Jacobson v. Massachusetts, 197 U.S. 11, 38 (1905).
In 1922, the Court specifically addressed the subject of school vaccination, holding that it is a valid exercise of the state’s police power to make vaccination a condition of attending public or private school. Zucht v. King, 260 U.S. 174 (1922). (more…)
In November, the journal Pediatrics published an entire supplement devoted to Pediatric Use of Complementary and Alternative Medicine: Legal, Ethical and Clinical Issues in Decision-Making. The authors purport to have “examined current legal, ethical, and clinical issues that arise when considering CAM use for children and identified where gaps remain in law and policy.” (S150) Their aim is to “illustrate the relevance and impact of identified [ethical, legal and clinical] guidelines and principles,” to recommend responses, identify issues needing further consideration, and thus “assist decision makers and act as a catalyst for policy development.” (S153)
Unfortunately, as we saw in Pediatrics & “CAM” I: the wrong solution, the authors’ solution for the “issues that arise when considering CAM use for children” consist, in the main, of placing a huge burden on the practicing physician to be knowledgeable about CAM, keep up with CAM research, educate patients about CAM, warn patients about CAM dangers, refer to CAM practitioners, ensure that CAM practitioners are properly educated, trained and credentialed, and so on.
Limit CAM? Not happening
Curiously absent are recommendations placing responsibility on those who profit from the sale of CAM products and services — the dietary supplement manufacturers, homeopaths, acupuncturists, and the like — whose actions are directly responsible for the deleterious effects on patients’ health detailed in the supplement articles and described in the earlier post.
Apparently the authors’ view is that there is no accommodation to CAM too onerous to ask the practicing physician or the patient to bear. Even though they plainly locate the problems they describe — a missed diagnosis, ineffective treatments, drug therapy interactions, poor advice — in the CAM services and products themselves, suggesting that these services and products be limited or eliminated never seems to cross their minds.
A recent announcement is likely to generate a lot of controversy. The Advisory Committee on Immunization Practices of the CDC has recommended that boys and young men be vaccinated against human papillomavirus (HPV). Previously the guidelines said boys “could” be given the HPV vaccine. Now they have recommended that boys age 11 to 12 “should” be vaccinated, as well as boys age 13 to 21 who have not already had the full series of 3 shots. The vaccine can also be given to boys as young as 9 and to young men age 22 to 26.
The vaccine was originally promoted as a way to prevent cervical cancer. Boys don’t have a cervix, so why should they be subjected to a “girl’s” vaccine? There are some good science-based reasons:
Boys can transmit the virus to female sex partners later in life, leading to cervical cancer in women.
More importantly, boys themselves can also be directly harmed by the virus. It can cause genital warts, cancer of the head and neck (tongue, tonsils and throat), anal and penile cancer, respiratory papillomatosis, and giant condyloma of Buschke and Lowenstein. In rare cases, immunocompromised patients can develop epidermodysplasia verruciformis.
Some of these conditions are not common, and the most common one, genital warts, may sound trivial. But “a picture is worth a thousand words,” so here is a link to a picture of a giant condyloma of Buschke and Lowenstein as an example of what HPV can do to the unvaccinated. The picture is not pleasant. If you are squeamish, you may not want to look at it. If you can’t even stand to look at it, imagine how devastating it would be to have it appear on your own body, and how nice it would be to be vaccinated against it.
We sense from the very first sentence that we are in familiar territory:
Rapid increases the use of complementary and alternative medicine (CAM) raise important legal, ethical, clinical, and policy issues. (S150)
“Rapid increases”? And evidence of these “rapid increases?” None cited.
We do, however, see the same shopworn reference to popularity deconstructed elsewhere on SBM. What we learned by actually examining “the large 2007 US survey” which purportedly “revealed that ~4 in 10 adults and 1 in 9 children and youth used CAM products or therapies within the previous year”(S150) is that
…most hard-core CAM modalities are used by a very small percentage of the population. Most are less than five percent. Only massage and manipulation are greater than 10 percent. These numbers are also not significantly different from 10 or 20 years ago — belying the claim that CAM use is increasing.
I’ve heard it said (actually, I’ve said it myself) that if you don’t have the science and evidence to back up your point of view, in order to persuade someone, make a movie. At least, this seems to be the philosophy of a number of cranks who have produced movies promoting pseudoscience over the last five years or so. The first one of these movies that really caught my attention was an anti-evolution, pro-”intelligent design” creationism documentary narrated by Ben Stein and released in 2008, Expelled: No Intelligence Allowed. The movie was pure creationist propaganda, complete with Ben Stein visiting Auschwitz and Dachau, the better to try to link “Darwinism” to the Holocaust.
Movies promoting religious pseudoscience such as intelligent design creationism are not the only kinds of pseudoscience propaganda films. Indeed, medicine is rife with them, and Wally Sampson has referred to this particularly pernicious genre of documentary as “medical propaganda films.” During the existence of this blog, we’ve reviewed a few such films (or at least written about what we could find out about them without paying for the DVD). For example, I’ve written about The Beautiful Truth, a paean to the Gerson protocol for cancer, complete with coffee enemas, and reviewed Simply Raw: Reversing Diabetes in 30 Days, a film dedicated to the claim that you can cure almost everything (including not just type II but type I diabetes) with a raw vegan diet. Harriet reviewed The Living Matrix: A Film on the New Science of Healing, a movie promoting “energy medicine” quackery. There’s even a film out now praising Stanley Burzynski and his highly dubious “antineoplaston” therapy that I’ve been meaning to review. I finally found a free copy of it to watch, and perhaps I’ll get to it before the end of the month. In the meantime, there’s a documentary people have been begging me to check out called The Greater Good that has been making the rounds of various film festivals and will be debuting at the IFC Center in New York on November 18. The very fact that Joe Mercola has hosted the movie streaming on his website in celebration of what he and Barbara Loe Fisher have dubbed “Vaccine Awareness Week” should tell you all you need to know about the movie.
I’m going to tell you more, though, because I’ve actually managed to sit through the whole thing. The things I do for my readers! To give you an idea of what you’re in for (in case the video is no longer available by the time that you read this), here’s the trailer:
The first thing I noticed about The Greater Good is that it’s slick and very well produced—considerably better produced, I think, than Expelled! The only aspect of it that I found annoying (besides the sheer quantity of anti-vaccine misinformation, pseudoscience, talking points, and distortions, all of which were plenty annoying) was the little animated segments. (Well, the little animated segments and any segment featuring Dr. Bob Sears.) However, given the sheer mass of anti-vaccine propaganda contained within this documentary, quibbling about a stylistic element like that is rather like quibbling about the arrangement of the deck chairs on the Titanic.
The documentary is structured, as many documentaries are, around three families, the better to provide the human interest “hook” for the rest of the story. Interspersed with segments about each family are interviews with various experts. Perhaps I should say two experts arrayed against a whole lot of “experts,” because defending vaccines we have real experts like Dr. Paul Offit; Dr. Melinda Wharton of the CDC; Dr. Norman Baylor, who is Director of the Office of Vaccines Research and Review in the FDA’s Center for Biologics Evaluation and Research; and Dr. Mark B. Feinberg, Vice President for Medical Affairs and Policy for Merck Vaccines and Infectious Diseases at Merck & Co., Inc. Arrayed against them we have a whole lot of anti-vaccine pseudoexperts, such as Barbara Loe Fisher, grande dame of the anti-vaccine movement and founder of the Orwellian-named National Vaccine Information Center (NVIC); Dr. Bob Sears, a pediatrician known for his non-science-based “alternative” vaccination schedule, who of late appears to have ceased mere flirting with the anti-vaccine movement and thrown his lot in with it; Dr. Lawrence Palevsky, a “wholistic” pediatrician; Dr. John Green III, who is described as a “specialist in clinical ecology and nutritional medicine“; and several trial lawyers known for representing parents suing for “vaccine injury,” lawyers such as Clifford Shoemaker, Kevin Conway, and Renee Gentry. (more…)
Normally, we don’t post on weekends on this particular blog, mainly because most of our readership visits during the week and we don’t have enough bloggers to cover the weekend reliably anyway. However, occasionally something happens that’s so bizarre, so worrisom that we can’t wait until Monday. I don’t even care if I’m late to the party after Tara, Mike the Mad Biologist, The Biology Files, Todd, and probably several others whom I’ve missed.
Regular readers of this blog and anyone who’s ever followed the anti-vaccine movement more than superficially have probably heard of pox parties. These are, yes, parties where parents who don’t want to vaccinate their children against chickenpox, hoping for “natural immunity,” expose their children who have never had chickenpox to children with active chickenpox in order to intentionally infect them with the disease. (Thanks, Mom and Dad, for a couple of weeks worth of misery and intense itching and a small chance of serious complications!) Although there might have been a weak rationale for such activities back before there was a vaccine for chickenpox, today pox parties are about as dumb a concept as I can think of and only make sense in the context of equally idiotic anti-vaccine pseudoscience, and apparently, as is the case with many idiotic things, has co-opted Facebook and other discussion forums as a means of getting like minded (if you can call what is behind this a “mind”) together for purposes of inflicting misery on their children. One such page even has a Quack Miranda-style warning: (more…)
I normally write the first draft of this blog the weekend before it is due, and this is no exception. However, I am ill this weekend. Headache, myalgias., painful cough, but only mildly ill. The worst part is the interferon induced brain fog; my thoughts flow with all the speed of pudding and I was not appreciably better as the week progressed, although no cracks about how you can’t any difference in my writing over baseline.
I doubt the cause of my symptoms is influenza. According to the CDC site and Google flu trends there is little influenza activity in the US at the moment, so it is probably one of the innumerable viruses that can cause a flu-like illness. I am also not ill enough to think I have influenza, but I could be having a modified course as I was vaccinated a month ago. Of course, the doctor who treats herself has a fool for a patient and an idiot for a doctor. Flu season approaches, so from my interferon addled brains, flu thoughts.
In 2000, a panel of experts was brought together by the Centers for Disease Control and Prevention (CDC). They came to discuss whether measles was still endemic in the United States, that is whether it still existed in the general background of US infectious diseases. They concluded that measles had been eradicated in the US, and that the occasional cases imported from abroad were stopped by a wall of vaccinated Americans.
Welcome to the future. The US is in the middle of its largest measles outbreak since 1996. Most of the cases originated abroad, brought back by unvaccinated travelers, either American residents or foreign visitors. This has so far led to 12 outbreaks (that is, a cluster of three or more connected cases) mostly among the unvaccinated. Of the 139 cases who were US residents rather than foreign visitors, twelve had documentation of adequate immunization.
The surprise isn’t that a few cases should slip through the wall of vaccination, but that the wall has so many chinks in it. The number of measles cases being imported, and the falling vaccination rates of Americans may reach the point soon where we no longer need to import our measles as it will once again become endemic.
Measles isn’t just a curious disease that we learned about in medical school (“cough, coryza, conjunctivits”); it’s a serious disease that leads to pneumonia in 1 in 20 children, and brain inflammation in 1 in 1000. Outside the US, it causes hundreds of thousands of deaths yearly.
We must increase our efforts to vaccinate all US residents properly (including undocumented residents). If measles does take hold once again in the U.S., the blame will fall squarely on our health care system’s failure to deliver vaccine, and on those who for whatever reason delay or avoid vaccination altogether.
It used to be that Americans viewed public health battles with excitement, a battle against fear itself, against the fear of children choking to death from whooping cough, or becoming paralyzed by polio. Now, as we sit behind our crumbling shield of vaccination, we have become complacent. If we fail to act, our complacency will be replaced by very real fears, especially for our children.
Evidently the 7 billionth human is going to be born on October 31. Happy birthday and welcome to the Earth. If you were unfortunate enough to be born into a developing country or a affluent California family, you may not receive your vaccinations, and may join one the 57 million who die each year of vaccine preventable diseases (VPD).
I totally misread the table. It’s about 4,320,000 who die of VPD. Well, I said I was no damn good at stats.
And if you are doubly unlucky, you may be exposed to illness from an unvaccinated friend, family or health care worker before you can get your vaccines, and join the ranks of the ‘only’s.’ The ‘only’s’ are those who die of vaccine preventable diseases and are mentioned in anti-vaccine literature in a sentence like ‘VPD X is a mild illness in most children and only kills Y% of cases ’. As I have said before the anti-vaxers do not care for whom the bell tolls.
I am no good at statistics. I signed up for, and dropped, statistics at least 4 times in college. Once they got past the bell shaped curve, it was one incomprehensible huh? Part of the problem with statistical concepts such as risks, both relative and absolute, is that it is often impossible to get a feel from what they represent. For me it is like metric measurements. I know what a 8 mile hike represents, but not an 8 kilometer hike. Same with centigrade and liters. I have been unable to internalize what metric means in my daily life. (more…)