Category: Clinical Trials
Corrigendum. The week in review for 02/12/2017
The week in review. Chiropractic and stroke. Integrative Medical doctors don’t trust vaccines. Death from medical marijuana. Shilajit: compost or mulch oozing from Himalayan rocks. India goes full Tuskeegee with AIDS. And more!
Re-thinking Antioxidant Supplementation for Macular Degeneration
After the AREDS trial, people with moderate to severe age-related macular degeneration were advised to take dietary supplements to slow the progression of the disease. But some experts say the trial actually showed supplements don't work, and might even make some patients worse.
Donald Trump versus the FDA: Is the standard of evidence for drug approval actually too low rather than too high?
All of the candidates being considered by President Trump for FDA Commissioner believe that the FDA is too strict in its standards for approving new drugs. In a commentary in Nature last week, two bioethicists argued that, at least in terms of preclinical data, the standard of evidence is actually too low. Which is correct?
Corrigendum. The week in SBM for 1.22.2017
Not every article and study that pops up my feeds in the world of pseudo-medicine is worthy of a complete blog post. But they need to be noticed and commented upon: Liver toxicity from herbs. Popped lungs from acupuncture. Chiropractic does not help scoliosis. Yoga is just exercise. There are eight kinds of wind: Great Feathery Wind, Scheming Wind, Hard Wind, Great...
Chinese BioMedical Research: Sturgeon’s Law In Action
A Chinese government investigation has found that 80%, yes eighty percent, of Chinese biomedical research is fabricated. I bet that is an underestimate for Traditional Chinese Pseudo-Medicine.
Myths integrative medicine sells us: “We never advocate alternative medicine without conventional medicine”
"Integrative medicine" (IM) effectively integrates quackery with real medicine. The main talking point by advocates of IM meant to deflect this criticism is that IM practitioners always use alternative medicine with conventional medicine and never advocate the use of alternative medicine alone. A new book by a prominent advocate of IM suggests that this talking point is at best self-delusion among academics...
Acupuncture’s Big Myth
The great acupuncture myth? No spoilers from me. Read the entry or skip to the penultimate paragraph to find out.
Son of (the unethical and unscientific) Trial To Assess Chelation Therapy rears its ugly head to the tune of $37 million
First, the NCCIH and NHLBI spend $30 million on a clinical trial of quackery for cardiovascular disease that produces predictably negative to at best equivocal results. Then that result, apparently, is enough to justify wasting another $37 million on a followup study—while dozens of other deserving studies go unfunded. Meanwhile STAT News lionizes the principal investigator of both trials as a brave...
Medical science policy in the U.S. under Donald Trump
The election of Donald Trump was unexpected. Given Trump's history of antivaccine beliefs and conspiracy theories, coupled with a fervor for deregulation (a fervor shared by the Republican Congress), it is reasonable to fear what will happen to medical science policy during the next four years.
Spinal Manipulation for Back and Neck Pain: Does It Work? Annotated.
Spinal Manipulation for Back and Neck Pain: Does It Work? You would think it does if you read the article but not if you actually read the literature.